The expression of TCR function depend on the gene rearrangement during ontogeny in nor-mal t cell.
细胞抗原受体(TCR)功能的表达有赖于该基因在正常T淋巴细胞发育过程中的重排。
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T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
The detection of TCRgene rearrangement has an important role in the study of the pathogenesis, classification, diagnosis and monitoring of prognosis of CTCL.