"This is the first major study that shows how small changes in one master regulator gene can cause a cascade of other metabolic effects in other genes," said lead author Tim Spector in a statement.
Conclusions AS an upstream regulator, PASG can regulate expression of a series of cell proliferation, differentiation relevant downstream genes through changing methylation levels of genomic DNA.
结论PASG基因作为上游调控基因，通过改变基因组甲基化水平调控下游一系列细胞增殖分化相关基因表达。
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In plants, these REDOX changes regulate the conformation of NPR1, a master regulator of salicylic acid (sa) - mediated defense genes.