In short, SUMO helps the PRC1 complex repress genes, and SENP2 reverses this repression, allowing gene transcription and expression.
总之,相扑帮助PRC1复合体抑制基因,SENP2逆转这种抑制,使得基因转录和表达。
2
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.