Also, disclosed are diagnostic methods for detecting a mutation in the G-proteincoupledreceptor nucleic acid sequences and an altered level of the soluble form of the receptors.
Receptor tyrosine kinases (RTK), Gprotein-coupled receptors (GPCR) and ion channel receptors are main cell surface receptors.
酪氨酸激酶型受体、G蛋白偶联受体和离子通道型受体是细胞表面三类主要受体。
3
CCR5, a membrane protein on cell surface, is a member of the Gprotein-coupledreceptor superfamily and one of the major co-receptors for HIV-1infection.