Some of the mice also had defective versions of the tumor suppressor genep53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
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Normally zebrafish, which carry the same p53gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.
In the latest study, the scientists used a genetic trick to make zebrafish turn green when the p53gene was switched on to explore the way it was regulated.