Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal genelinkage not equilibrium and and emergence clinical effect.
结论在染色体异常核型中,均有不同程度的基因缺失,造成基因连锁的不平衡,因而出现一些临床效应。
3
Linkage disequilibrium analysis is a effective way to identify the function of the of the gene (or targeted high-resolution QTL).