Trastuzumab is a humanised antibody, designed to target and block the function of HER2, a protein produced by a specific gene with cancer-causing potential.
Objective To study the feasibility of adenoviral transduction of Herceptin complete antibody gene and its effect on Her2 over expressing cancer.
目的探讨应用基因治疗方法表达完全抗体的可行性及其对肿瘤的治疗作用。
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Objective To clone human epidermal growth factor receptor (HER2) gene and establish a MCF-7 cell line with stable co-expression of HER2 and estrogen receptor (ER).