The results show that the stable leu2 mutants have been constructed successfully by one-step genedisruption.
结果表明，用一步基因中断法成功地建立了稳定的LEU2基因突变体。
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Most importantly, such a precise genedisruption in the nervous system will allow us to study specific roles of candidate genes in neurodegenerative diseases that afflict the aging.
It is marked by a mutation in a gene known as RPE65 which results in a missing enzyme that leads to degradation of the retina and the disruption of vision processing in the brain.