GangliosideGM3 has been proved to be a physiological cell differentiation inducer in several human leukemia cell lines. However, the inducing differentiation mechanism of GM3 remains unclear.
The kinetic study of the incorporation of exogenous gangliosideGM3 into the lipid bilayer of rabbit sarcoplasmic reticulum (SR) was carried out by trace extraction of Gls and high performance TLC.