Objective: To study the effects of high concentration glucose on islet cell apoptosis and apoptosis related genes, and discuss the glucosetoxicity and its molecular mechanism.
目的:观察高浓度葡萄糖体外对胰岛细胞凋亡及凋亡相关基因表达的影响,探讨葡萄糖毒性及其分子机制。
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Insulin is effective, it ACTS synergistically with oral metformin to reduce glucosetoxicity, and it sends the adolescent a message that this is a disease to be taken seriously.
The effects of hyperglycemia on calcium load and cyclic AMP content in skeletal muscle may accord with its anti-insulin action, which may be involved in the mechanism of glucosetoxicity.