Lower starting doses may be required for patients with renal or hepaticimpairment and elderly patients.
低起始剂量对肾或肝损伤患者及老年患者很有必要。
2
Use cautiously in patients at risk for increased bleeding from trauma, surgery, or other pathologic conditions and in those with severe hepaticimpairment.
对创伤,外科手术,或其他病理状态以及严重肝功能损害的患者慎用。
3
Neurocognitive impairment in liver patients is called hepatic encephalopathy.