This finding suggests ways to improve anxiolytics and to develop drugs for other neurological disorders based on their specificity for GABA(A) receptor subtypes in distinct neuronal circuits.
The molecule blocked a gene that codes for areceptor for GABA, a brain signaling molecule.
该分子抑制了产生氨基丁酸受体这种大脑内信号分子的基因片段。
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Methods: The patch clamp was used to record the changes in average whole cell current and the conductance of GABA-Areceptor on cultured hippocampal neurons in different developing stages.