A new HPLC method with fluorescence detector was developed and validated for the simultaneous determination of dextrorphan and guaifenesin in human plasma.
These appear today on medications that include dextromethorphan, a cough suppressant, the expectorant guaifenesin and the decongestants phenylephrine and pseudoephedrine.
如今，镇咳药右美沙芬、祛痰药愈创甘油醚以及解充血药苯福林和伪麻黄硷的包装盒上就标注了警告。
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OBJECTIVE To establish a LC-MS/MS method for the simultaneous determination of guaifenesin, bromhexine, ambroxol in human plasma and to study their pharmacokinetics in healthy volunteers.