But at present, many anti idiotypic antibodies are mouse original antibodies, which can cause humanantimouseantibody (HAMA) response and decrease the curative effect.
但由于目前所使用的抗独特型抗体多为鼠源性，用于人体可产生人抗鼠抗体反应，从而影响疗效。
2
Results the detector plate only reacted with the anti-brucella antibody to show a specific reaction and showed no cross-reaction with anti-tubercle bacillus antibody or normal human and mouse samples.
In order to reduce the humanantimouseantibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.