In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.

In 2005, researchers at Sloan-Kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as P53, was turned off.

Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.