ObjectiveTo investigate the effects of fluoxetine on the hypothalamus-pituitary-adrenalaxis(HPA) in type 2 diabetic patients with depression and to evaluate their clinic significance.
目的探讨氟西汀对2型糖尿病合并抑郁症患者的下丘脑垂体肾上腺轴（HPA）功能的影响及其临床意义。
2
DATA SYNTHESIS: Acute stress affected the immune system mainly by inducing the changes of organism through hypothalamus-pituitary-adrenal cortex axis and sympathetic nervous system.
资料综合：急性应激主要通过下丘脑-垂体-肾上腺皮质轴和交感神经系统引起机体免疫系统的变化。
3
Objective:To investigate the variations of hypothalamuspituitaryadrenalaxis(HPA) in type 2 diabetic patients and those with depression and to evaluate their clinic significance.