Objective To investigate the genetic polymorphism of HLA-B locus in Guangdong Han population and compare the characteristic of the allele frequency distribution with that in other populations.
目的调查广东汉族人群HLA-B位点基因多态性，比较不同人群HLA-B等位基因频率分布特征。
2
Methods A simple, rapid and sensitive poly-nuclear cell assay was used to investigate the frequency of HPRT locus mutation.
方法采用多核细胞法研究肿瘤患者外周血淋巴细胞HPRT基因位点的突变频率，并与正常人群进行对比。
3
The relatively complete theory of frequency method and root locus method for the design of automatic control system was set up through the efforts of numerous scholars after world war II.