Conclusion Tumor is adapted to hypoxic microenvironment through HIF1 pathway after hepatic arterial blockage.
结论肝动脉阻断后缺氧微环境刺激肿瘤细胞通过HIF - 1通路产生适应性改变。
2
The transcription factor hypoxia-inducible factor 1 (HIF1) has been implicated in regulating many of the genes that are responsible for the metabolic difference.