ObjectiveTo make Singopicroside hydrophilic gel matrix tablets and to examine the factors affecting their dissolution rates.

Results the nifedipine sustained-release beads was hydrophilic gel frame, drug diffusion and frame erosion was the release mechanisms in vitro.

Hydroxypropylmethylcellulose(HPMC), as hydrophilic gel matrix, is widely applied in the study of controlled release and sustained release preparations.