Erythroid-specific 5-aminolevulinate synthase (ALAS2) catalyzes the rate-limiting step in heme biosynthesis of erythroidcells.
红系特异的5-氨基酮戊酸合成酶（ALAS2）是红系细胞血红素生物合成的限速酶。
2
Methods Induce the differentiation of erythroleukemia cell line HB60-5 to mature erythroidcells by altering the culture condition and plot a cell growth curve.
方法利用红白血病细胞株hb60 - 5的生长特性，通过改变培养条件，促使细胞向成熟细胞分化。
3
The absence of ALAS2 leads to maturation arrest of primitive erythroidcells. Heritable mutations of ALAS2 gene are responsible for the human X-linked sideroblastic anemia (XLSA).