Conclusion: in vitro high glucose solution increased mesangial cell synthesis of extracellularmatrixproteins.
结论:体外高糖可增加细胞外基质蛋白的合成。
2
The recent studies demonstrate that cytogenetic alterations, oncogenes, tumor suppressor genes, adhesion molecules and extracellularmatrixproteins may play important roles in the process.
The tumor cells produce a whole range of proteases that degrade the proteins of the extracellularmatrix that hems them in, part of which is the basement membrane.