Excessive focal pressure developed during the midstance and heel-rise parts of the gait cycle may cause skin loss or hypertrophy of the stratum corneum (callus) over bony prominences.
这样，在步态的中端和足跟抬升期会产生过量的局部压力，可能造成在骨突起部位的脱皮或角质增生。
2
Muscular biopsy revealed focal necrotic muscle with loss of muscle fibers, thickened walls of small blood vessels and occasionally thrombosis in capillary.
肌肉活检可见灶性肌纤维坏死，肌纤维横纹消失，小血管壁增厚，个别毛细血管内血栓形成。
3
Focal neurological features including hemiparesis, sensory loss, visual field deficits.