The paper takes wreath epoxy chloropropane, bisulfitesodium as raw material, the adopting two methods to synthesize 2,3-oxiranemethane sulfonic acid sodium salt;
以环氧氯丙烷、亚硫酸氢钠为原料，采用两步法合成2，3-环氧丙磺酸钠；
2
In the presence of water, the sodium metabisulfite produces sodiumbisulfite.
焦亚硫酸钠在遇水之后会产生亚硫酸氢钠。
3
Conclusion: This specific and efficient HPLC method can be used for the quality control of andrographolide sodiumbisulfite.