Over his career, his 35 broken bones made the Guinness Book of Records; his body rattled with pins and plates, and it seemed preposterous that he should have died in his bed, of pulmonary fibrosis.

At high concentrations, it can cause significant acute disease with pulmonary edema, whereas chronic exposures at lower concentrations can lead to significant pulmonary fibrosis.

Objective: to observe the effect of inhaled budesonide on pulmonary fibrosis induced by bleomycin in rats and to explore its mechanism.