Objective to investigate the effect of flutamide on laryngeal carcinoma cell lines HEP-2 apoptosis.
目的观察氟硝丁酰胺对喉鳞癌细胞株hep 2的生长调控作用。
2
Furthermore, androgen up-regulation of intracellular ar protein was partially inhibited (50%) by nonsteroidal androgen antagonist, flutamide.
雄激素拮抗剂氟他胺也能够部分抑制(5 0 %)睾酮对细胞内AR蛋白水平的上调作用。
3
CONCLUSIONS Androgen can autoregulate the expression of androgen receptor in MCF-7 breast cancer cell line. Flutamide and hydroxyflutamide up regulate the expression of androgen receptor.