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单词 cytochalasin
释义

Definition of cytochalasin in English:

cytochalasin

noun ˌsʌɪtəʊkəˈleɪsɪnˌsīdəkəˈlās(ə)n
mass nounBiochemistry
  • Any of a group of polycyclic compounds produced by fungi, used experimentally in research for their property of interfering with cell processes.

    Example sentencesExamples
    • Cells at a reduced cholesterol concentration were treated with cytochalasin D.
    • In experiments that test the effect of actin, cells were incubated for 30 min before experiments in medium containing 20 M cytochalasin D to disrupt actin filaments.
    • At low concentrations, cytochalasin D is reported to inhibit actin polymerization.
    • In stark contrast to cytochalasin, treatment with nocodazole did not produce a loss of any features; instead there was an increase in the density of filaments.
    • We measured the effect of cytochalasin D mobilization of integrins on adhesion of a leukocyte cell line to both cultured endothelium and purified ligand substrates.

Origin

1960s: from cyto- 'cell' + Greek khalasis 'dislocation'.

Definition of cytochalasin in US English:

cytochalasin

nounˌsīdəkəˈlās(ə)n
Biochemistry
  • Any of a group of polycyclic compounds produced by fungi, used experimentally in research for their property of interfering with cell processes.

    Example sentencesExamples
    • At low concentrations, cytochalasin D is reported to inhibit actin polymerization.
    • Cells at a reduced cholesterol concentration were treated with cytochalasin D.
    • In experiments that test the effect of actin, cells were incubated for 30 min before experiments in medium containing 20 M cytochalasin D to disrupt actin filaments.
    • In stark contrast to cytochalasin, treatment with nocodazole did not produce a loss of any features; instead there was an increase in the density of filaments.
    • We measured the effect of cytochalasin D mobilization of integrins on adhesion of a leukocyte cell line to both cultured endothelium and purified ligand substrates.

Origin

1960s: from cyto- ‘cell’ + Greek khalasis ‘dislocation’.

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更新时间:2024/12/27 5:20:08