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单词 transactivation
释义

Definition of transactivation in English:

transactivation

noun ˌtrɑːns--nz-ˌtransaktɪˈveɪʃ(ə)ntranˌsaktəˈvāSHən
mass nounBiochemistry
  • Activation of a gene at one locus by the presence of a particular gene at another locus, typically following infection by a virus.

    〔生化〕反式激活(作用),转活

    Example sentencesExamples
    • Thus, transactivation may account for most of the GC side effects, such as diabetes, arterial hypertension, edema, and glaucoma.
    • These injurious substances have been reported to activate EGFR through direct ligand-mediated activation, or via transactivation.
    • In mouse pituitary gonadotrope cells, MMP2 and MMP9 can mediate EGFR transactivation.
    • The timing of these events is complex and it should be noted that the transactivation of stress-inducible genes is not fully understood even in model systems.
    • The differential transactivation potential of various HIV - 1 subtypes on these viruses needs to be explored.

Definition of transactivation in US English:

transactivation

nountranˌsaktəˈvāSHən
Biochemistry
  • Activation of a gene at one locus by the presence of a particular gene at another locus, typically following infection by a virus.

    〔生化〕反式激活(作用),转活

    Example sentencesExamples
    • These injurious substances have been reported to activate EGFR through direct ligand-mediated activation, or via transactivation.
    • The differential transactivation potential of various HIV - 1 subtypes on these viruses needs to be explored.
    • The timing of these events is complex and it should be noted that the transactivation of stress-inducible genes is not fully understood even in model systems.
    • Thus, transactivation may account for most of the GC side effects, such as diabetes, arterial hypertension, edema, and glaucoma.
    • In mouse pituitary gonadotrope cells, MMP2 and MMP9 can mediate EGFR transactivation.
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更新时间:2025/1/30 21:21:17