A mutation in which a sense codon that corresponds to one of the twenty amino acids specified by the genetic code is changed to a chain-terminating codon.
〔遗传〕无义突变
Example sentencesExamples
The first spans codons 195-196 and induces a silent substitution at codon 195 and a nonsense mutation at codon 196.
The proximity of the nonsense mutation to the start codon indicates that these mutations are null alleles.
Another nonsense mutation at codon 187 is shared by the human, the chimpanzee and the gorilla, so that it is most likely to have occurred in their ancestral species.
A nonsense mutation is represented by a solid red circle.
Another mutant isolated from the screen, LPY727, contained a nonsense mutation at amino acid 15.
Definition of nonsense mutation in US English:
nonsense mutation
noun
Genetics
A mutation in which a sense codon that corresponds to one of the twenty amino acids specified by the genetic code is changed to a chain-terminating codon.
〔遗传〕无义突变
Example sentencesExamples
The first spans codons 195-196 and induces a silent substitution at codon 195 and a nonsense mutation at codon 196.
Another mutant isolated from the screen, LPY727, contained a nonsense mutation at amino acid 15.
A nonsense mutation is represented by a solid red circle.
The proximity of the nonsense mutation to the start codon indicates that these mutations are null alleles.
Another nonsense mutation at codon 187 is shared by the human, the chimpanzee and the gorilla, so that it is most likely to have occurred in their ancestral species.