Definition of provirus in English:

provirus

noun prəʊˈvʌɪrəsprōˈvīrəs

Microbiology

The genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell.
〔微生物〕原病毒，病毒原，前病毒
Example sentencesExamples
- The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
- Once integrated with the host's genetic material, the DNA version of the retroviral RNA is called a provirus.
- HERV-W proviruses probably entered the genome of primates before the split between Old World and New World monkeys.
- Both retrovirus-like organization and expression are typical of the functional gypsy proviruses that have inserted recently into the euchromatic DNA of some strains.
- Recombination requires the simultaneous infection of a cell with two different proviruses, allowing the encapsulation of one RNA transcript from each provirus into a heterozygous virion.

Derivatives

proviral

adjective

Microbiology

It is generally admitted that these Human Endogenous RetroViruses derive originally from rare events of germ-line infections by exogenous retroviruses leading to proviral DNA integration.
Example sentencesExamples
- Endogenous retroviruses are the proviral form of exogenous retroviruses that have become integrated into the germ line of the host.
- Identification of clonal proviral insertions by oncogenic retroviruses has led to the isolation of novel tumor-associated genes.
- To identify expressed sequences, 16 kb of genomic DNA flanking the proviral integration site was sequenced and compared to genetic databases.
- Emery et al 40 found that, at autopsy, the presence of HHV - 6 DNA was associated with significant increases in HIV - 1 proviral DNA.

Definition of provirus in US English:

provirus

nounprōˈvīrəs

Microbiology

The genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell.
〔微生物〕原病毒，病毒原，前病毒
Example sentencesExamples
- HERV-W proviruses probably entered the genome of primates before the split between Old World and New World monkeys.
- Once integrated with the host's genetic material, the DNA version of the retroviral RNA is called a provirus.
- Recombination requires the simultaneous infection of a cell with two different proviruses, allowing the encapsulation of one RNA transcript from each provirus into a heterozygous virion.
- The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
- Both retrovirus-like organization and expression are typical of the functional gypsy proviruses that have inserted recently into the euchromatic DNA of some strains.

单词	provirus
释义	Definition of provirus in English: provirus noun prəʊˈvʌɪrəsprōˈvīrəs Microbiology The genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell. 〔微生物〕原病毒，病毒原，前病毒 Example sentencesExamples The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene. Once integrated with the host's genetic material, the DNA version of the retroviral RNA is called a provirus. HERV-W proviruses probably entered the genome of primates before the split between Old World and New World monkeys. Both retrovirus-like organization and expression are typical of the functional gypsy proviruses that have inserted recently into the euchromatic DNA of some strains. Recombination requires the simultaneous infection of a cell with two different proviruses, allowing the encapsulation of one RNA transcript from each provirus into a heterozygous virion. Derivatives proviral adjective Microbiology It is generally admitted that these Human Endogenous RetroViruses derive originally from rare events of germ-line infections by exogenous retroviruses leading to proviral DNA integration. Example sentencesExamples Endogenous retroviruses are the proviral form of exogenous retroviruses that have become integrated into the germ line of the host. Identification of clonal proviral insertions by oncogenic retroviruses has led to the isolation of novel tumor-associated genes. To identify expressed sequences, 16 kb of genomic DNA flanking the proviral integration site was sequenced and compared to genetic databases. Emery et al 40 found that, at autopsy, the presence of HHV - 6 DNA was associated with significant increases in HIV - 1 proviral DNA. Definition of provirus in US English: provirus nounprōˈvīrəs Microbiology The genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell. 〔微生物〕原病毒，病毒原，前病毒 Example sentencesExamples HERV-W proviruses probably entered the genome of primates before the split between Old World and New World monkeys. Once integrated with the host's genetic material, the DNA version of the retroviral RNA is called a provirus. Recombination requires the simultaneous infection of a cell with two different proviruses, allowing the encapsulation of one RNA transcript from each provirus into a heterozygous virion. The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene. Both retrovirus-like organization and expression are typical of the functional gypsy proviruses that have inserted recently into the euchromatic DNA of some strains.
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