A compound present (in the form of highly carcinogenic esters) in croton oil.
〔化〕佛波醇
A tetracyclic alcohol; chemical formula: C₂₀H₂₈O₆
Example sentencesExamples
This is in striking contrast to phorbol esters, which mimic G q pathway-produced DAG and cause strongly hyperactive locomotion within 1-2 hr of omnidirectional contact.
Twenty-four hours after transfection, cells were stimulated with ionomycin, phorbol 12-myristate 13-acetate, and calcium chloride.
Various studies on the active principles of the manchineel tree have shown tigliane phorbol esters to be the likely cause of the severe reactions.
When the phorbol ester TPA is added to MCF - 7 cells, a dramatic increase in the invasiveness and the metastatic potential of these cells occurs.
Neutrophils stimulated to respiratory burst by phorbol myristate acetate activate IQ, and inhibitor studies have identified myeloperoxidase as the enzyme responsible.