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单词 leukotriene
释义

Definition of leukotriene in English:

leukotriene

noun ˌluːkə(ʊ)ˈtrʌɪiːnˌlo͞okəˈtrīēn
Biochemistry
  • Any of a group of biologically active compounds, originally isolated from leucocytes. They are metabolites of arachidonic acid, containing three conjugated double bonds.

    Example sentencesExamples
    • In addition to chemokines, lipid metabolites such as leukotrienes and prostaglandins are emerging as important upstream controllers of DC migration toward LNs.
    • Arachidonic acid metabolites such as leukotrienes and thromboxanes have been shown to increase in the lung during ischemia-reperfusion injury in a dog model of warm ischemia.
    • Prostaglandins and leukotrienes from arachidonic acid metabolism are highly inflammatory molecules, and play an important role in the pathophysiology of asthma.
    • During the early phase, mast cells release mediators (e.g., histamine, leukotrienes, prostaglandins and thromboxanes) that lead to vasodilation, edema and bronchoconstriction.
    • These breakdown products can become toxic to the membrane due to excess levels of free radicals, lipid peroxides, and arachidonic acid and its metabolites such as leukotrienes.

Definition of leukotriene in US English:

leukotriene

nounˌlo͞okəˈtrīēn
Biochemistry
  • Any of a group of biologically active compounds, originally isolated from leukocytes. They are metabolites of arachidonic acid, containing three conjugated double bonds.

    Example sentencesExamples
    • In addition to chemokines, lipid metabolites such as leukotrienes and prostaglandins are emerging as important upstream controllers of DC migration toward LNs.
    • During the early phase, mast cells release mediators (e.g., histamine, leukotrienes, prostaglandins and thromboxanes) that lead to vasodilation, edema and bronchoconstriction.
    • Prostaglandins and leukotrienes from arachidonic acid metabolism are highly inflammatory molecules, and play an important role in the pathophysiology of asthma.
    • Arachidonic acid metabolites such as leukotrienes and thromboxanes have been shown to increase in the lung during ischemia-reperfusion injury in a dog model of warm ischemia.
    • These breakdown products can become toxic to the membrane due to excess levels of free radicals, lipid peroxides, and arachidonic acid and its metabolites such as leukotrienes.
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更新时间:2024/11/11 7:58:26