释义 |
Definition of agonist in English: agonistnoun ˈaɡənɪstˈæɡənəst 1Biochemistry A substance which initiates a physiological response when combined with a receptor. 〔生化〕兴奋剂。比较 ANTAGONIST Compare with antagonist Example sentencesExamples - For example, the highly potent opioid receptor agonist etorphine is not a medically useful drug because it can only be used a few times before the body becomes desensitized to the drug.
- Medications that can reduce androgen levels include estrogen, gonadotropin-releasing hormone agonists, and glucocorticoids.
- These observations provide support for the model that glucose and structurally related sugars are agonists of the Gpr1 receptor.
- They may mimic naturally occurring steroids, act as hormone receptor agonists or antagonists or alter the enzymes responsible for hormone synthesis and degradation.
- Opioid receptor agonists act at sites that are distributed throughout this circuit to produce analgesia.
2Anatomy A muscle whose contraction moves a part of the body directly. 〔剖〕主缩肌,主动肌。比较 ANTAGONIST as modifier there is a failure to select the right agonist muscles Compare with antagonist Example sentencesExamples - It's a matter of muscle aesthetics: The upper arm looks best when both its opposing muscle groups, the agonists and antagonists - that's bis and tris to you - carry a complementary amount of muscle.
- In addition, we believe that the agonist / antagonist muscle ratios are important values when considering how the scapula provides stability, mobility, and symptom-free function.
- Alternate between agonist and antagonist muscle groups (e.g… quadriceps and hamstrings), and alternate sides.
- Muscles may act as agonists, antagonists, synergics and fixators.
- The agonist and antagonist muscles work in concert to create muscular balance in the human body.
3 another term for protagonist Example sentencesExamples - To every agonist, there is an antagonist.
- But now, replying to Haraphas taunts with a startling invitation to combat, Samson is confident as the agonist was never before depicted.
Derivativesnoun An agonist is described as a drug that binds to and activates receptors; the possibility of spontaneous receptor activity and therefore of inverse agonism is not mentioned. Example sentencesExamples - Rather, all known abused drugs affect a limited number of neurotransmitters by agonism or antagonism of a specific receptor site.
- Pharmacologically, it is characterized by the constitutive activity of the ligand-free receptor, and by the inverse, partial, and full agonism due to the bound ligand.
- Studies have clearly demonstrated that key therapies in the acute attack of migraine share the common pharmacologic activity of serotonin receptor agonism.
OriginEarly 20th century: from Greek agōnistēs 'contestant' (a sense reflected in English in the early 17th century), from agōn 'contest'. Definition of agonist in US English: agonistnounˈæɡənəstˈaɡənəst 1Biochemistry A substance which initiates a physiological response when combined with a receptor. 〔生化〕兴奋剂。比较 ANTAGONIST Compare with antagonist Example sentencesExamples - These observations provide support for the model that glucose and structurally related sugars are agonists of the Gpr1 receptor.
- For example, the highly potent opioid receptor agonist etorphine is not a medically useful drug because it can only be used a few times before the body becomes desensitized to the drug.
- Opioid receptor agonists act at sites that are distributed throughout this circuit to produce analgesia.
- Medications that can reduce androgen levels include estrogen, gonadotropin-releasing hormone agonists, and glucocorticoids.
- They may mimic naturally occurring steroids, act as hormone receptor agonists or antagonists or alter the enzymes responsible for hormone synthesis and degradation.
2Anatomy A muscle whose contraction moves a part of the body directly. 〔剖〕主缩肌,主动肌。比较 ANTAGONIST as modifier there is a failure to select the right agonist muscles Often contrasted with antagonist Example sentencesExamples - It's a matter of muscle aesthetics: The upper arm looks best when both its opposing muscle groups, the agonists and antagonists - that's bis and tris to you - carry a complementary amount of muscle.
- Muscles may act as agonists, antagonists, synergics and fixators.
- Alternate between agonist and antagonist muscle groups (e.g… quadriceps and hamstrings), and alternate sides.
- In addition, we believe that the agonist / antagonist muscle ratios are important values when considering how the scapula provides stability, mobility, and symptom-free function.
- The agonist and antagonist muscles work in concert to create muscular balance in the human body.
3 another term for protagonist Example sentencesExamples - But now, replying to Haraphas taunts with a startling invitation to combat, Samson is confident as the agonist was never before depicted.
- To every agonist, there is an antagonist.
OriginEarly 20th century: from Greek agōnistēs ‘contestant’ (a sense reflected in English in the early 17th century), from agōn ‘contest’. |