A narcotic and hallucinogenic compound found in the fly agaric and other fungi.
〔化〕毒蝇蕈醇,氨甲基羟异噁唑
An alkaloid related to oxazole; chemical formula: C₄H₆N₂O₂
Example sentencesExamples
Microinjections of muscimol and bicuculline into the pontine reticular formation modify the sleep-waking cycle in the rat.
The administration of muscimol inhibited the development of reverse tolerance against morphine hyperactivity in mice that had received chronic administration of morphine.
Eugster and Waser first isolated muscimol from this species and it is this substance which is the main hallucinogen.
Indeed, benzodiazepines can interact with other neurotransmitters within the DPAG and, compared to muscimol, can exert different actions on heterogeneous GABAA receptor subtypes.
The substances were GABA, a GABA-enhancing compound called muscimol, and a GABA-blocking compound called bicuculline.
Origin
1960s: from modern Latin muscaria(see muscarine) + im(ine)+ -ol.