Definition of pathogenicity island in English:

pathogenicity island

noun

Genetics

单词	pathogenicity island
释义	Definition of pathogenicity island in English: pathogenicity island noun Genetics A series of contiguous genes in a pathogenic microorganism including one or more that determines virulence, acquired by horizontal gene transfer. 〔遗传〕病原性基因岛，致病岛，毒力岛 Example sentencesExamples Its genetic code is embedded in a complex DNA structure called the TCP pathogenicity island. The genes encoding the attaching and effacing (A / E) phenotype are situated on a 43 kb pathogenicity island. The ability of EPEC to adhere to the cells and produce A / E lesions has been attributed to the genes encoded on the pathogenicity island. Salmonella can sense bile in the intestine and use it as a signal to downregulate secretion and invasion genes of pathogenicity island. This suggests diversity in mechanisms or specificities of pathogenicity island acquisition.
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