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单词 methotrexate
释义

Definition of methotrexate in English:

methotrexate

noun ˌmɛθəˈtrɛkseɪtˌmiːθəˈtrɛkseɪtˌmeTHəˈtreksāt
mass nounMedicine
  • A synthetic compound that interferes with cell growth and is used to treat leukaemia and other forms of cancer.

    〔医〕氨甲蝶呤(抗肿瘤药)

    Chemical formula: C₂₀H₂₂N₈O₅

    Example sentencesExamples
    • The patient was treated with methotrexate and leukovorin calcium, and tumor lysis syndrome with acute renal failure occurred.
    • Cancer drugs used for primary bone cancer include methotrexate, doxorubicin, and cisplatin.
    • Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.
    • Treatment may include systemic steroids, intralesional steroid injection, antimalarials, or methotrexate.
    • Another combination is methotrexate plus cyclo-sporine and methotrexate.

Origin

1950s: from meth- (denoting a substance containing methyl groups) + elements of unknown origin.

Definition of methotrexate in US English:

methotrexate

nounˌmeTHəˈtreksāt
Medicine
  • A synthetic compound that interferes with cell growth and is used to treat leukemia and other forms of cancer.

    〔医〕氨甲蝶呤(抗肿瘤药)

    Alternative name: 4-amino-10-methylfolic acid; chemical formula: C₂₀H₂₂N₈O₅

    Example sentencesExamples
    • The patient was treated with methotrexate and leukovorin calcium, and tumor lysis syndrome with acute renal failure occurred.
    • Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.
    • Treatment may include systemic steroids, intralesional steroid injection, antimalarials, or methotrexate.
    • Cancer drugs used for primary bone cancer include methotrexate, doxorubicin, and cisplatin.
    • Another combination is methotrexate plus cyclo-sporine and methotrexate.

Origin

1950s: from meth- (denoting a substance containing methyl groups) + elements of unknown origin.

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更新时间:2024/12/27 3:20:25