Definition of determination in English:

determination

noun dɪˌtəːmɪˈneɪʃ(ə)ndəˌtərməˈneɪʃ(ə)n

mass noun

1The quality of being determined; firmness of purpose.
those who succeed because of sheer grit and determination
Example sentencesExamples
- The chance was there and I had a go and, although it didn't work out, I've got the grit and determination to succeed.
- So could she ever go back to just enjoying sailing without the goal-setting, ambitious drive and determination to set records and win races?
- Her trainers believe that she has the ability, commitment and determination to realise her Olympic dream but she will need a little financial help to get there.
- I would not be here today if it had not been for their sheer determination to find me.
- There is also something admirable about the slow pace of change in the U.S. quality media and their determination to hang onto the tried and tested formulas.
- The king's undeniable ruthlessness can be seen either as needless brutality, or as necessitous firmness in his utter determination to achieve total victory.
- And the union's determination to push its social agenda into schools is driving significant numbers of parents to withdraw their children from public schools.
- His unflinching determination to take the time he needed to reach a considered decision marked him out as an unusual talent and in the process he upgraded the standing of referees within the game.
- His determination to improve the quality of colonial workmanship and to impose a businesslike system of payments incurred many enemies.
- Turkey, perhaps, deserved the victory more by showing more purpose and determination to get forward than their African opponents.
- This is an amazing school, defying its size through sheer determination to make the most of school life, through sporting activities, projects and school tours.
- She described the book as ‘a fine history of stern stuff, independence - of sheer determination to survive’.
- He has the grit and determination to drive the atomic research centre towards its stated goal.
- Sometimes we make our achievements possible not by brilliance or talent but by the sheer, dogged determination that leads us to get up each day and try again.
- Since he was elected president of the Russian Federation, he has often publicly assured journalists of his determination to respect their independence.
- They haven't been particularly good, but there has been a robustness and determination to them; qualities lacking earlier in the season.
- Reform of the banking sector becomes an acid test of this government's determination to change public perception of its competence and its commitment to competition.
- His leadership qualities and determination to challenge capitalism earned him lasting respect from all who knew him, particularly in his role as union steward and factory convenor.
- The boys can however, be proud of their display and they showed great grit and determination to make a contest of it against much more physical and stronger opponents.
- There is no drive, commitment or determination to do anything worthwhile on the pitch.
Synonyms
resolution, resolve, resoluteness
will power, strength of will, strength of character, single-mindedness, sense of purpose, firmness of purpose, fixity of purpose, purposefulness
intentness, decision, decidedness
steadfastness, staunchness, perseverance, persistence, indefatigability, tenacity, tenaciousness, staying power, strong-mindedness, backbone, the bulldog spirit, pertinacity, pertinaciousness
stubbornness, doggedness, obstinacy, obdurateness, obduracy, inflexibility
spiritedness, braveness, bravery, boldness, courage, courageousness, pluck, pluckiness, stout-heartedness
British Dunkirk spirit
German sitzfleisch
informal guts, spunk, grit, stickability
North American informal stick-to-it-iveness
archaic intension
rare perseveration
2The process of establishing something exactly by calculation or research.
测定，确定（多指通过计算或研究得到的结论）
determination of molecular structures
对分子结构的确定。
Example sentencesExamples
- The second part of the evaluation process is the determination of healthfulness of the products one is forced to eat when meat, etc. products are eliminated.
- This makes determination of the local protein concentration difficult.
- There is no acceptance of the place of performance assessment within career structures for teachers and in the accepted processes for the determination of rewards.
- The key is that their development should be a matter for local determination.
- However, proteins sharing the same fold can have different functions, and structure determination and analysis will not always mean that function can be derived.
- Other methods of molecular weight determination include gel permeation chromatography, end-group analysis, and osmometry.
- Histopathologic verification of malignancy remains essential for a firm diagnosis and determination of appropriate therapy.
- These calculations lead to the determination of the product's value-based price, which in the figure is just above $200.
- To date, this has hindered determination of the molecular structure of the pigments.
- Explanation is substituted for deduction, prediction, solution, determination and calculation as the objectives of science.
- For he explained the process of wage determination in full, whereas the later version was simply a theory of the demand for labour.
- Among the important results of their study is the role played by education in the wage determination process.
- It is founded on a misconception of the role of consumption rather than production in the income determination process.
- The tariffs are subject to final determination next month.
- Postpartum interval was calculated by the determination of plasma progesterone concentrations.
- They suggested the government give financial support to local investors in the service sector and oversee service price determination by local and foreign operators.
- This grouping was done to establish the final cohorts that would permit comparison and allow determination of the utilization of order sets.
- This fundamental research work enables the determination of biological endpoints, which can be used to set up in vitro tests.
- Further data processing (calibration, determination of peak area, averaging, etc.) is done by computer.
- It is therefore fair to say that, as a consequence of the integration process, trade union behaviour in the wage determination process has become interrelated across member states.
Synonyms
calculation, discovery, ascertainment, establishment, fixing, deduction, divination, diagnosis, discernment, check, verification, confirmation
1. 2.1Law The settlement of a dispute by the authoritative decision of a judge or arbitrator.
  〔律〕（法官或仲裁人对争议的）裁定
  expert determination
  基因对性别的决定。
  Example sentencesExamples
  It would be artificial to do so in the circumstances, pending the arbitrators' determination of the matters that are within their jurisdiction.
  Is Ontario the appropriate and convenient forum for determination of the issues raised and claims advanced by Banks in his amended statement of claim?
  It does, however, with the authority of the Act, lay the ground for enforcement by the provision that until final determination of the dispute the decision is binding.
  So far as our claim for damages pursuant to those undertakings are concerned, the order I seek is for it to be remitted to a judge for determination.
  The purpose of section 73 is to require the claimants to bring all claims in one appeal, and to achieve finality in determination of that single appeal.
2. 2.2Law count noun A judicial decision or sentence.
  〔律〕司法裁决；判决
  Example sentencesExamples
  The previous determination may include a settlement.
  I have to say that I find the Agency's stance on the Wretton determination surprising.
  At paragraph 16 of his determination the Adjudicator concluded that he accepted Dr Gallwey's assessment.
  Since that time the applicants have been contesting that determination.
  If this court is satisfied that the judge's determination was wrong, it must allow this appeal.
3The controlling or deciding of the nature or outcome of something.
（对事物本质或结果的）控制；决定
genetic sex determination
基因对性别的决定。
Example sentencesExamples
- We assume that control of sex determination in the ancestor of Drosophila was through heterogamety at the dsx locus.
- Simplified model for control of germline sex determination in C. elegans.
- As well as being useful, the tra mutations were obviously relevant to the developmental genetics of males and to sex determination in general.
- Biologist Jack Frazier pointed out that the temperature around the eggs during the incubation is critical in sex determination.
- These are the basic questions to be solved to understand the genetic mechanisms of sex determination and their evolution.
- Several hypotheses have been proposed to explain the mechanism of such sex determination, including control at a single polymorphic locus.
- Chromosomal sex determination can also be more complex, with multiple X and Y chromosomes, or maternal, as in the carrion fly Chrysomya rufifacies.
- When sex determination is under zygotic control, the probability of an individual being male depends upon its genotype rather than that of its mother.
- Hence, Sxl does not appear to play the key discriminating role in controlling sex determination and dosage compensation in sciarids that it plays in Drosophila.
- Were changes in protein sequence required for XSE gene products to interact with Sxl Pe, and if so, are these new residues important only for sex determination?
- In mammals, male sex determination is triggered by a primary signal, encoded by the testis determining factor SRY, localized on the Y chromosome.
- This indicates that the maternal Odsm1 genotype itself, rather than the genotype of the offspring, controls the sex determination.
- Sexual behavior in Drosophila is under the control of the sex determination pathway.
- Another classic fish model for studying genetic sex determination is the medaka Oryzias latipes.
- Our results support the idea that divergent tra homologs might control sex determination in yet other dipteran species, where a dsx gene has been identified.
- In some dioecious species, sex determination is controlled by genes on sex chromosomes.
- SRY controls sex determination not just in humans and mice but in many other mammals, from dogs to kangaroos.
- Did anyone mention a sharp declining male-female ratio, existing female infanticide and increased selective abortion of the female fetus through sex determination?
- The gene doublesex of Drosophila is the last gene in the genetic cascade that controls sex determination.
- Diploid males have subsequently been found in many species of Hymenoptera and have been taken as evidence for the widespread occurrence of this method of sex determination.
Synonyms
setting, fixing, specification, a decision about, settlement, designation, allotment, arrangement, choice, naming, nomination, appointment, establishment, authorization, prescription
4Law
The cessation of an estate or interest.
〔律〕（财产权、利息的）终止
Example sentencesExamples
- It however now seems clear, from a case in Yelverton, that the assignment by the tenant at will of his interest to a third party is no determination of the tenancy, unless the lessor at will have notice.
- Thus during the war a lease could have been granted for 10 years with a provision for determination if the war ended earlier, and this would satisfy the rule in Lace v Chantler.
5archaic A tendency to move in a fixed direction.
〈古〉（向固定方向）移动的趋势
Example sentencesExamples
- Second, retained membranes and septic substances result in a determination of blood to the uterus.
- The image of God in which man was created did not consist in an inclination and determination of the will to holiness.

Origin

Late Middle English (in the senses 'settlement of a controversy by a judge or by reasoning' and 'authoritative opinion'): via Old French from Latin determinatio(n-), from the verb determinare (see determine).

Definition of determination in US English:

determination

noundəˌtərməˈnāSH(ə)ndəˌtərməˈneɪʃ(ə)n

1Firmness of purpose; resoluteness.
（目的的）坚定不移；坚决；果断
he advanced with an unflinching determination
Example sentencesExamples
- So could she ever go back to just enjoying sailing without the goal-setting, ambitious drive and determination to set records and win races?
- The boys can however, be proud of their display and they showed great grit and determination to make a contest of it against much more physical and stronger opponents.
- His determination to improve the quality of colonial workmanship and to impose a businesslike system of payments incurred many enemies.
- Since he was elected president of the Russian Federation, he has often publicly assured journalists of his determination to respect their independence.
- His unflinching determination to take the time he needed to reach a considered decision marked him out as an unusual talent and in the process he upgraded the standing of referees within the game.
- Reform of the banking sector becomes an acid test of this government's determination to change public perception of its competence and its commitment to competition.
- The chance was there and I had a go and, although it didn't work out, I've got the grit and determination to succeed.
- And the union's determination to push its social agenda into schools is driving significant numbers of parents to withdraw their children from public schools.
- There is no drive, commitment or determination to do anything worthwhile on the pitch.
- I would not be here today if it had not been for their sheer determination to find me.
- Turkey, perhaps, deserved the victory more by showing more purpose and determination to get forward than their African opponents.
- This is an amazing school, defying its size through sheer determination to make the most of school life, through sporting activities, projects and school tours.
- She described the book as ‘a fine history of stern stuff, independence - of sheer determination to survive’.
- His leadership qualities and determination to challenge capitalism earned him lasting respect from all who knew him, particularly in his role as union steward and factory convenor.
- He has the grit and determination to drive the atomic research centre towards its stated goal.
- There is also something admirable about the slow pace of change in the U.S. quality media and their determination to hang onto the tried and tested formulas.
- They haven't been particularly good, but there has been a robustness and determination to them; qualities lacking earlier in the season.
- Her trainers believe that she has the ability, commitment and determination to realise her Olympic dream but she will need a little financial help to get there.
- The king's undeniable ruthlessness can be seen either as needless brutality, or as necessitous firmness in his utter determination to achieve total victory.
- Sometimes we make our achievements possible not by brilliance or talent but by the sheer, dogged determination that leads us to get up each day and try again.
Synonyms
resolution, resolve, resoluteness
2The process of establishing something exactly by calculation or research.
测定，确定（多指通过计算或研究得到的结论）
determination of molecular structures
对分子结构的确定。
Example sentencesExamples
- To date, this has hindered determination of the molecular structure of the pigments.
- There is no acceptance of the place of performance assessment within career structures for teachers and in the accepted processes for the determination of rewards.
- Histopathologic verification of malignancy remains essential for a firm diagnosis and determination of appropriate therapy.
- The key is that their development should be a matter for local determination.
- Other methods of molecular weight determination include gel permeation chromatography, end-group analysis, and osmometry.
- This fundamental research work enables the determination of biological endpoints, which can be used to set up in vitro tests.
- For he explained the process of wage determination in full, whereas the later version was simply a theory of the demand for labour.
- The second part of the evaluation process is the determination of healthfulness of the products one is forced to eat when meat, etc. products are eliminated.
- It is founded on a misconception of the role of consumption rather than production in the income determination process.
- Explanation is substituted for deduction, prediction, solution, determination and calculation as the objectives of science.
- They suggested the government give financial support to local investors in the service sector and oversee service price determination by local and foreign operators.
- This grouping was done to establish the final cohorts that would permit comparison and allow determination of the utilization of order sets.
- Postpartum interval was calculated by the determination of plasma progesterone concentrations.
- This makes determination of the local protein concentration difficult.
- Among the important results of their study is the role played by education in the wage determination process.
- These calculations lead to the determination of the product's value-based price, which in the figure is just above $200.
- Further data processing (calibration, determination of peak area, averaging, etc.) is done by computer.
- It is therefore fair to say that, as a consequence of the integration process, trade union behaviour in the wage determination process has become interrelated across member states.
- However, proteins sharing the same fold can have different functions, and structure determination and analysis will not always mean that function can be derived.
- The tariffs are subject to final determination next month.
Synonyms
calculation, discovery, ascertainment, establishment, fixing, deduction, divination, diagnosis, discernment, check, verification, confirmation
1. 2.1Law The settlement of a dispute by the authoritative decision of a judge or arbitrator.
  〔律〕（法官或仲裁人对争议的）裁定
  Example sentencesExamples
  It does, however, with the authority of the Act, lay the ground for enforcement by the provision that until final determination of the dispute the decision is binding.
  Is Ontario the appropriate and convenient forum for determination of the issues raised and claims advanced by Banks in his amended statement of claim?
  So far as our claim for damages pursuant to those undertakings are concerned, the order I seek is for it to be remitted to a judge for determination.
  The purpose of section 73 is to require the claimants to bring all claims in one appeal, and to achieve finality in determination of that single appeal.
  It would be artificial to do so in the circumstances, pending the arbitrators' determination of the matters that are within their jurisdiction.
2. 2.2Law A judicial decision or sentence.
  〔律〕司法裁决；判决
  Example sentencesExamples
  Since that time the applicants have been contesting that determination.
  If this court is satisfied that the judge's determination was wrong, it must allow this appeal.
  I have to say that I find the Agency's stance on the Wretton determination surprising.
  The previous determination may include a settlement.
  At paragraph 16 of his determination the Adjudicator concluded that he accepted Dr Gallwey's assessment.
3The controlling or deciding of something's nature or outcome.
（对事物本质或结果的）控制；决定
genetic sex determination
基因对性别的决定。
Example sentencesExamples
- Another classic fish model for studying genetic sex determination is the medaka Oryzias latipes.
- When sex determination is under zygotic control, the probability of an individual being male depends upon its genotype rather than that of its mother.
- As well as being useful, the tra mutations were obviously relevant to the developmental genetics of males and to sex determination in general.
- This indicates that the maternal Odsm1 genotype itself, rather than the genotype of the offspring, controls the sex determination.
- Hence, Sxl does not appear to play the key discriminating role in controlling sex determination and dosage compensation in sciarids that it plays in Drosophila.
- Diploid males have subsequently been found in many species of Hymenoptera and have been taken as evidence for the widespread occurrence of this method of sex determination.
- Did anyone mention a sharp declining male-female ratio, existing female infanticide and increased selective abortion of the female fetus through sex determination?
- Simplified model for control of germline sex determination in C. elegans.
- In mammals, male sex determination is triggered by a primary signal, encoded by the testis determining factor SRY, localized on the Y chromosome.
- Were changes in protein sequence required for XSE gene products to interact with Sxl Pe, and if so, are these new residues important only for sex determination?
- Our results support the idea that divergent tra homologs might control sex determination in yet other dipteran species, where a dsx gene has been identified.
- We assume that control of sex determination in the ancestor of Drosophila was through heterogamety at the dsx locus.
- The gene doublesex of Drosophila is the last gene in the genetic cascade that controls sex determination.
- In some dioecious species, sex determination is controlled by genes on sex chromosomes.
- Biologist Jack Frazier pointed out that the temperature around the eggs during the incubation is critical in sex determination.
- Several hypotheses have been proposed to explain the mechanism of such sex determination, including control at a single polymorphic locus.
- These are the basic questions to be solved to understand the genetic mechanisms of sex determination and their evolution.
- SRY controls sex determination not just in humans and mice but in many other mammals, from dogs to kangaroos.
- Sexual behavior in Drosophila is under the control of the sex determination pathway.
- Chromosomal sex determination can also be more complex, with multiple X and Y chromosomes, or maternal, as in the carrion fly Chrysomya rufifacies.
Synonyms
setting, fixing, specification, a decision about, settlement, designation, allotment, arrangement, choice, naming, nomination, appointment, establishment, authorization, prescription
4Law
The cessation of an estate or interest.
〔律〕（财产权、利息的）终止
Example sentencesExamples
- It however now seems clear, from a case in Yelverton, that the assignment by the tenant at will of his interest to a third party is no determination of the tenancy, unless the lessor at will have notice.
- Thus during the war a lease could have been granted for 10 years with a provision for determination if the war ended earlier, and this would satisfy the rule in Lace v Chantler.
5archaic A tendency to move in a fixed direction.
〈古〉（向固定方向）移动的趋势
Example sentencesExamples
- Second, retained membranes and septic substances result in a determination of blood to the uterus.
- The image of God in which man was created did not consist in an inclination and determination of the will to holiness.

Origin

Late Middle English (in the senses ‘settlement of a controversy by a judge or by reasoning’ and ‘authoritative opinion’): via Old French from Latin determinatio(n-), from the verb determinare (see determine).

单词	determination
释义	Definition of determination in English: determination noun dɪˌtəːmɪˈneɪʃ(ə)ndəˌtərməˈneɪʃ(ə)n mass noun 1The quality of being determined; firmness of purpose. those who succeed because of sheer grit and determination Example sentencesExamples The chance was there and I had a go and, although it didn't work out, I've got the grit and determination to succeed. So could she ever go back to just enjoying sailing without the goal-setting, ambitious drive and determination to set records and win races? Her trainers believe that she has the ability, commitment and determination to realise her Olympic dream but she will need a little financial help to get there. I would not be here today if it had not been for their sheer determination to find me. There is also something admirable about the slow pace of change in the U.S. quality media and their determination to hang onto the tried and tested formulas. The king's undeniable ruthlessness can be seen either as needless brutality, or as necessitous firmness in his utter determination to achieve total victory. And the union's determination to push its social agenda into schools is driving significant numbers of parents to withdraw their children from public schools. His unflinching determination to take the time he needed to reach a considered decision marked him out as an unusual talent and in the process he upgraded the standing of referees within the game. His determination to improve the quality of colonial workmanship and to impose a businesslike system of payments incurred many enemies. Turkey, perhaps, deserved the victory more by showing more purpose and determination to get forward than their African opponents. This is an amazing school, defying its size through sheer determination to make the most of school life, through sporting activities, projects and school tours. She described the book as ‘a fine history of stern stuff, independence - of sheer determination to survive’. He has the grit and determination to drive the atomic research centre towards its stated goal. Sometimes we make our achievements possible not by brilliance or talent but by the sheer, dogged determination that leads us to get up each day and try again. Since he was elected president of the Russian Federation, he has often publicly assured journalists of his determination to respect their independence. They haven't been particularly good, but there has been a robustness and determination to them; qualities lacking earlier in the season. Reform of the banking sector becomes an acid test of this government's determination to change public perception of its competence and its commitment to competition. His leadership qualities and determination to challenge capitalism earned him lasting respect from all who knew him, particularly in his role as union steward and factory convenor. The boys can however, be proud of their display and they showed great grit and determination to make a contest of it against much more physical and stronger opponents. There is no drive, commitment or determination to do anything worthwhile on the pitch. Synonyms resolution, resolve, resoluteness will power, strength of will, strength of character, single-mindedness, sense of purpose, firmness of purpose, fixity of purpose, purposefulness intentness, decision, decidedness steadfastness, staunchness, perseverance, persistence, indefatigability, tenacity, tenaciousness, staying power, strong-mindedness, backbone, the bulldog spirit, pertinacity, pertinaciousness stubbornness, doggedness, obstinacy, obdurateness, obduracy, inflexibility spiritedness, braveness, bravery, boldness, courage, courageousness, pluck, pluckiness, stout-heartedness British Dunkirk spirit German sitzfleisch informal guts, spunk, grit, stickability North American informal stick-to-it-iveness archaic intension rare perseveration 2The process of establishing something exactly by calculation or research. 测定，确定（多指通过计算或研究得到的结论） determination of molecular structures 对分子结构的确定。 Example sentencesExamples The second part of the evaluation process is the determination of healthfulness of the products one is forced to eat when meat, etc. products are eliminated. This makes determination of the local protein concentration difficult. There is no acceptance of the place of performance assessment within career structures for teachers and in the accepted processes for the determination of rewards. The key is that their development should be a matter for local determination. However, proteins sharing the same fold can have different functions, and structure determination and analysis will not always mean that function can be derived. Other methods of molecular weight determination include gel permeation chromatography, end-group analysis, and osmometry. Histopathologic verification of malignancy remains essential for a firm diagnosis and determination of appropriate therapy. These calculations lead to the determination of the product's value-based price, which in the figure is just above $200. To date, this has hindered determination of the molecular structure of the pigments. Explanation is substituted for deduction, prediction, solution, determination and calculation as the objectives of science. For he explained the process of wage determination in full, whereas the later version was simply a theory of the demand for labour. Among the important results of their study is the role played by education in the wage determination process. It is founded on a misconception of the role of consumption rather than production in the income determination process. The tariffs are subject to final determination next month. Postpartum interval was calculated by the determination of plasma progesterone concentrations. They suggested the government give financial support to local investors in the service sector and oversee service price determination by local and foreign operators. This grouping was done to establish the final cohorts that would permit comparison and allow determination of the utilization of order sets. This fundamental research work enables the determination of biological endpoints, which can be used to set up in vitro tests. Further data processing (calibration, determination of peak area, averaging, etc.) is done by computer. It is therefore fair to say that, as a consequence of the integration process, trade union behaviour in the wage determination process has become interrelated across member states. Synonyms calculation, discovery, ascertainment, establishment, fixing, deduction, divination, diagnosis, discernment, check, verification, confirmation 2.1Law The settlement of a dispute by the authoritative decision of a judge or arbitrator. 〔律〕（法官或仲裁人对争议的）裁定 expert determination 基因对性别的决定。 Example sentencesExamples It would be artificial to do so in the circumstances, pending the arbitrators' determination of the matters that are within their jurisdiction. Is Ontario the appropriate and convenient forum for determination of the issues raised and claims advanced by Banks in his amended statement of claim? It does, however, with the authority of the Act, lay the ground for enforcement by the provision that until final determination of the dispute the decision is binding. So far as our claim for damages pursuant to those undertakings are concerned, the order I seek is for it to be remitted to a judge for determination. The purpose of section 73 is to require the claimants to bring all claims in one appeal, and to achieve finality in determination of that single appeal. 2.2Law count noun A judicial decision or sentence. 〔律〕司法裁决；判决 Example sentencesExamples The previous determination may include a settlement. I have to say that I find the Agency's stance on the Wretton determination surprising. At paragraph 16 of his determination the Adjudicator concluded that he accepted Dr Gallwey's assessment. Since that time the applicants have been contesting that determination. If this court is satisfied that the judge's determination was wrong, it must allow this appeal. 3The controlling or deciding of the nature or outcome of something. （对事物本质或结果的）控制；决定 genetic sex determination 基因对性别的决定。 Example sentencesExamples We assume that control of sex determination in the ancestor of Drosophila was through heterogamety at the dsx locus. Simplified model for control of germline sex determination in C. elegans. As well as being useful, the tra mutations were obviously relevant to the developmental genetics of males and to sex determination in general. Biologist Jack Frazier pointed out that the temperature around the eggs during the incubation is critical in sex determination. These are the basic questions to be solved to understand the genetic mechanisms of sex determination and their evolution. Several hypotheses have been proposed to explain the mechanism of such sex determination, including control at a single polymorphic locus. Chromosomal sex determination can also be more complex, with multiple X and Y chromosomes, or maternal, as in the carrion fly Chrysomya rufifacies. When sex determination is under zygotic control, the probability of an individual being male depends upon its genotype rather than that of its mother. Hence, Sxl does not appear to play the key discriminating role in controlling sex determination and dosage compensation in sciarids that it plays in Drosophila. Were changes in protein sequence required for XSE gene products to interact with Sxl Pe, and if so, are these new residues important only for sex determination? In mammals, male sex determination is triggered by a primary signal, encoded by the testis determining factor SRY, localized on the Y chromosome. This indicates that the maternal Odsm1 genotype itself, rather than the genotype of the offspring, controls the sex determination. Sexual behavior in Drosophila is under the control of the sex determination pathway. Another classic fish model for studying genetic sex determination is the medaka Oryzias latipes. Our results support the idea that divergent tra homologs might control sex determination in yet other dipteran species, where a dsx gene has been identified. In some dioecious species, sex determination is controlled by genes on sex chromosomes. SRY controls sex determination not just in humans and mice but in many other mammals, from dogs to kangaroos. Did anyone mention a sharp declining male-female ratio, existing female infanticide and increased selective abortion of the female fetus through sex determination? The gene doublesex of Drosophila is the last gene in the genetic cascade that controls sex determination. Diploid males have subsequently been found in many species of Hymenoptera and have been taken as evidence for the widespread occurrence of this method of sex determination. Synonyms setting, fixing, specification, a decision about, settlement, designation, allotment, arrangement, choice, naming, nomination, appointment, establishment, authorization, prescription 4Law The cessation of an estate or interest. 〔律〕（财产权、利息的）终止 Example sentencesExamples It however now seems clear, from a case in Yelverton, that the assignment by the tenant at will of his interest to a third party is no determination of the tenancy, unless the lessor at will have notice. Thus during the war a lease could have been granted for 10 years with a provision for determination if the war ended earlier, and this would satisfy the rule in Lace v Chantler. 5archaic A tendency to move in a fixed direction. 〈古〉（向固定方向）移动的趋势 Example sentencesExamples Second, retained membranes and septic substances result in a determination of blood to the uterus. The image of God in which man was created did not consist in an inclination and determination of the will to holiness. Origin Late Middle English (in the senses 'settlement of a controversy by a judge or by reasoning' and 'authoritative opinion'): via Old French from Latin determinatio(n-), from the verb determinare (see determine). Definition of determination in US English: determination noundəˌtərməˈnāSH(ə)ndəˌtərməˈneɪʃ(ə)n 1Firmness of purpose; resoluteness. （目的的）坚定不移；坚决；果断 he advanced with an unflinching determination Example sentencesExamples So could she ever go back to just enjoying sailing without the goal-setting, ambitious drive and determination to set records and win races? The boys can however, be proud of their display and they showed great grit and determination to make a contest of it against much more physical and stronger opponents. His determination to improve the quality of colonial workmanship and to impose a businesslike system of payments incurred many enemies. Since he was elected president of the Russian Federation, he has often publicly assured journalists of his determination to respect their independence. His unflinching determination to take the time he needed to reach a considered decision marked him out as an unusual talent and in the process he upgraded the standing of referees within the game. Reform of the banking sector becomes an acid test of this government's determination to change public perception of its competence and its commitment to competition. The chance was there and I had a go and, although it didn't work out, I've got the grit and determination to succeed. And the union's determination to push its social agenda into schools is driving significant numbers of parents to withdraw their children from public schools. There is no drive, commitment or determination to do anything worthwhile on the pitch. I would not be here today if it had not been for their sheer determination to find me. Turkey, perhaps, deserved the victory more by showing more purpose and determination to get forward than their African opponents. This is an amazing school, defying its size through sheer determination to make the most of school life, through sporting activities, projects and school tours. She described the book as ‘a fine history of stern stuff, independence - of sheer determination to survive’. His leadership qualities and determination to challenge capitalism earned him lasting respect from all who knew him, particularly in his role as union steward and factory convenor. He has the grit and determination to drive the atomic research centre towards its stated goal. There is also something admirable about the slow pace of change in the U.S. quality media and their determination to hang onto the tried and tested formulas. They haven't been particularly good, but there has been a robustness and determination to them; qualities lacking earlier in the season. Her trainers believe that she has the ability, commitment and determination to realise her Olympic dream but she will need a little financial help to get there. The king's undeniable ruthlessness can be seen either as needless brutality, or as necessitous firmness in his utter determination to achieve total victory. Sometimes we make our achievements possible not by brilliance or talent but by the sheer, dogged determination that leads us to get up each day and try again. Synonyms resolution, resolve, resoluteness 2The process of establishing something exactly by calculation or research. 测定，确定（多指通过计算或研究得到的结论） determination of molecular structures 对分子结构的确定。 Example sentencesExamples To date, this has hindered determination of the molecular structure of the pigments. There is no acceptance of the place of performance assessment within career structures for teachers and in the accepted processes for the determination of rewards. Histopathologic verification of malignancy remains essential for a firm diagnosis and determination of appropriate therapy. The key is that their development should be a matter for local determination. Other methods of molecular weight determination include gel permeation chromatography, end-group analysis, and osmometry. This fundamental research work enables the determination of biological endpoints, which can be used to set up in vitro tests. For he explained the process of wage determination in full, whereas the later version was simply a theory of the demand for labour. The second part of the evaluation process is the determination of healthfulness of the products one is forced to eat when meat, etc. products are eliminated. It is founded on a misconception of the role of consumption rather than production in the income determination process. Explanation is substituted for deduction, prediction, solution, determination and calculation as the objectives of science. They suggested the government give financial support to local investors in the service sector and oversee service price determination by local and foreign operators. This grouping was done to establish the final cohorts that would permit comparison and allow determination of the utilization of order sets. Postpartum interval was calculated by the determination of plasma progesterone concentrations. This makes determination of the local protein concentration difficult. Among the important results of their study is the role played by education in the wage determination process. These calculations lead to the determination of the product's value-based price, which in the figure is just above $200. Further data processing (calibration, determination of peak area, averaging, etc.) is done by computer. It is therefore fair to say that, as a consequence of the integration process, trade union behaviour in the wage determination process has become interrelated across member states. However, proteins sharing the same fold can have different functions, and structure determination and analysis will not always mean that function can be derived. The tariffs are subject to final determination next month. Synonyms calculation, discovery, ascertainment, establishment, fixing, deduction, divination, diagnosis, discernment, check, verification, confirmation 2.1Law The settlement of a dispute by the authoritative decision of a judge or arbitrator. 〔律〕（法官或仲裁人对争议的）裁定 Example sentencesExamples It does, however, with the authority of the Act, lay the ground for enforcement by the provision that until final determination of the dispute the decision is binding. Is Ontario the appropriate and convenient forum for determination of the issues raised and claims advanced by Banks in his amended statement of claim? So far as our claim for damages pursuant to those undertakings are concerned, the order I seek is for it to be remitted to a judge for determination. The purpose of section 73 is to require the claimants to bring all claims in one appeal, and to achieve finality in determination of that single appeal. It would be artificial to do so in the circumstances, pending the arbitrators' determination of the matters that are within their jurisdiction. 2.2Law A judicial decision or sentence. 〔律〕司法裁决；判决 Example sentencesExamples Since that time the applicants have been contesting that determination. If this court is satisfied that the judge's determination was wrong, it must allow this appeal. I have to say that I find the Agency's stance on the Wretton determination surprising. The previous determination may include a settlement. At paragraph 16 of his determination the Adjudicator concluded that he accepted Dr Gallwey's assessment. 3The controlling or deciding of something's nature or outcome. （对事物本质或结果的）控制；决定 genetic sex determination 基因对性别的决定。 Example sentencesExamples Another classic fish model for studying genetic sex determination is the medaka Oryzias latipes. When sex determination is under zygotic control, the probability of an individual being male depends upon its genotype rather than that of its mother. As well as being useful, the tra mutations were obviously relevant to the developmental genetics of males and to sex determination in general. This indicates that the maternal Odsm1 genotype itself, rather than the genotype of the offspring, controls the sex determination. Hence, Sxl does not appear to play the key discriminating role in controlling sex determination and dosage compensation in sciarids that it plays in Drosophila. Diploid males have subsequently been found in many species of Hymenoptera and have been taken as evidence for the widespread occurrence of this method of sex determination. Did anyone mention a sharp declining male-female ratio, existing female infanticide and increased selective abortion of the female fetus through sex determination? Simplified model for control of germline sex determination in C. elegans. In mammals, male sex determination is triggered by a primary signal, encoded by the testis determining factor SRY, localized on the Y chromosome. Were changes in protein sequence required for XSE gene products to interact with Sxl Pe, and if so, are these new residues important only for sex determination? Our results support the idea that divergent tra homologs might control sex determination in yet other dipteran species, where a dsx gene has been identified. We assume that control of sex determination in the ancestor of Drosophila was through heterogamety at the dsx locus. The gene doublesex of Drosophila is the last gene in the genetic cascade that controls sex determination. In some dioecious species, sex determination is controlled by genes on sex chromosomes. Biologist Jack Frazier pointed out that the temperature around the eggs during the incubation is critical in sex determination. Several hypotheses have been proposed to explain the mechanism of such sex determination, including control at a single polymorphic locus. These are the basic questions to be solved to understand the genetic mechanisms of sex determination and their evolution. SRY controls sex determination not just in humans and mice but in many other mammals, from dogs to kangaroos. Sexual behavior in Drosophila is under the control of the sex determination pathway. Chromosomal sex determination can also be more complex, with multiple X and Y chromosomes, or maternal, as in the carrion fly Chrysomya rufifacies. Synonyms setting, fixing, specification, a decision about, settlement, designation, allotment, arrangement, choice, naming, nomination, appointment, establishment, authorization, prescription 4Law The cessation of an estate or interest. 〔律〕（财产权、利息的）终止 Example sentencesExamples It however now seems clear, from a case in Yelverton, that the assignment by the tenant at will of his interest to a third party is no determination of the tenancy, unless the lessor at will have notice. Thus during the war a lease could have been granted for 10 years with a provision for determination if the war ended earlier, and this would satisfy the rule in Lace v Chantler. 5archaic A tendency to move in a fixed direction. 〈古〉（向固定方向）移动的趋势 Example sentencesExamples Second, retained membranes and septic substances result in a determination of blood to the uterus. The image of God in which man was created did not consist in an inclination and determination of the will to holiness. Origin Late Middle English (in the senses ‘settlement of a controversy by a judge or by reasoning’ and ‘authoritative opinion’): via Old French from Latin determinatio(n-), from the verb determinare (see determine).
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