Definition of osteoclast in English:

osteoclast

noun ˈɒstɪə(ʊ)klastˈɑstiəˌklæst

Physiology

A large multinucleate bone cell which absorbs bone tissue during growth and healing.
〔生理〕破骨细胞
Example sentencesExamples
- The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases.
- Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium.
- Williams also showed that genistein decreased acid secretion by osteoclasts, thus decreasing bone dissolution.
- Note the presence of numerous osteoclasts lining the bone trabeculae.
- They activate mature osteoclasts indirectly through osteoblasts, inhibit osteoclast cell death, and stimulate osteoclast progenitor formation.

Derivatives

osteoclastic

adjective

Physiology

The tunnel wall showed active remodeling, with areas of osteoclastic resorption and areas of new bone formation.
Example sentencesExamples
- There is usually scant osteoblastic or osteoclastic activity, and often there is a marrow component with fat or hematopoietic elements.
- At the cellular level, there was decreased osteoblastic and increased osteoclastic activity.
- The bones show increased vascularity, porosity, and osteoclastic activity, resulting in the thinning of cortical bone and loss of intramedullary trabecular bone.
- Bone mineral density is determined by the homeostasis between osteoblastic bone formation and osteoclastic bone resorption.

Origin

Late 19th century: from osteo- 'bone' + Greek klastēs 'breaker'.

Definition of osteoclast in US English:

osteoclast

nounˈɑstiəˌklæstˈästēəˌklast

Physiology

A large multinucleate bone cell which absorbs bone tissue during growth and healing.
〔生理〕破骨细胞
Example sentencesExamples
- Williams also showed that genistein decreased acid secretion by osteoclasts, thus decreasing bone dissolution.
- They activate mature osteoclasts indirectly through osteoblasts, inhibit osteoclast cell death, and stimulate osteoclast progenitor formation.
- Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium.
- Note the presence of numerous osteoclasts lining the bone trabeculae.
- The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases.

Origin

Late 19th century: from osteo- ‘bone’ + Greek klastēs ‘breaker’.

单词	osteoclast
释义	Definition of osteoclast in English: osteoclast noun ˈɒstɪə(ʊ)klastˈɑstiəˌklæst Physiology A large multinucleate bone cell which absorbs bone tissue during growth and healing. 〔生理〕破骨细胞 Example sentencesExamples The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases. Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium. Williams also showed that genistein decreased acid secretion by osteoclasts, thus decreasing bone dissolution. Note the presence of numerous osteoclasts lining the bone trabeculae. They activate mature osteoclasts indirectly through osteoblasts, inhibit osteoclast cell death, and stimulate osteoclast progenitor formation. Derivatives osteoclastic adjective Physiology The tunnel wall showed active remodeling, with areas of osteoclastic resorption and areas of new bone formation. Example sentencesExamples There is usually scant osteoblastic or osteoclastic activity, and often there is a marrow component with fat or hematopoietic elements. At the cellular level, there was decreased osteoblastic and increased osteoclastic activity. The bones show increased vascularity, porosity, and osteoclastic activity, resulting in the thinning of cortical bone and loss of intramedullary trabecular bone. Bone mineral density is determined by the homeostasis between osteoblastic bone formation and osteoclastic bone resorption. Origin Late 19th century: from osteo- 'bone' + Greek klastēs 'breaker'. Definition of osteoclast in US English: osteoclast nounˈɑstiəˌklæstˈästēəˌklast Physiology A large multinucleate bone cell which absorbs bone tissue during growth and healing. 〔生理〕破骨细胞 Example sentencesExamples Williams also showed that genistein decreased acid secretion by osteoclasts, thus decreasing bone dissolution. They activate mature osteoclasts indirectly through osteoblasts, inhibit osteoclast cell death, and stimulate osteoclast progenitor formation. Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium. Note the presence of numerous osteoclasts lining the bone trabeculae. The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases. Origin Late 19th century: from osteo- ‘bone’ + Greek klastēs ‘breaker’.
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