with every fibre of your beingliteraryEMOTIONAL if you feel something with every fibre of your being, you feel it very strongly 极其地，全身心地 He wanted her with every fibre of his being. 他一心一意地想要她。
with every fibre of your being• What she was sure of, though, was that she wanted him with every fibre of her being.• And in that moment she wished with every fibre of her being that it really was possible for her to stay away.
→ with every fibre of your being at fibre(2)