The company now has a large number of workers who feel badly let down.

公司的很多工人现在都感到非常沮丧。

The flat was really very nice, but compared with what we'd been used to, it was a terrible let-down.

这套公寓真的很不错，但比起我们以往住的地方，那就差太远了。

The sense of let-down today is all the greater because in the past doctors have been over-confident about these treatments.

医生们过去对这些疗法过度自信，导致今天的挫败感尤其强烈。