in charge of 1. 管理，照管，负责，指挥 An experienced engineer is in charge of the project. 一位有经验的工程师负责这项工程。 He placed his younger brother in charge of the lumberyard. 他安排他的弟弟管理贮木场。 Mary is in charge of the children. 玛丽负责照管这些孩子。 2. 受…管理，在…掌管(或照管)之下 The application should be kept in charge of the personnel office. 申请表应存在人事室。